"Praying in the Spirit"
Do you mean:
1-The 'Holy Ghost' possessing you, praying to his other 2 Fellow Gods/persons/natures?
2- Praying to it?
3- Or praying with Faith?
Scripture answers your question
1Cor 14:2 For one who speaks in a tongue speaks not to men
but to God; for no one understands him, but he utters mysteries in the Spirit.
1Cor 14:14 For if I pray in a tongue,
my spirit prays, but my mind is unfruitful.
Romans 8:26 Likewise the Spirit
helps us in our weakness. For we do not know what to pray for as we ought, but
the Spirit himself intercedes for us with groanings too deep for words.
27 And he who searches hearts knows what is the mind of the Spirit, because
the Spirit intercedes for the saints according to the will of God.
Romans 8:16 The Spirit himself
bears witness with our spirit that we are children of God,
Jude 1:20 But you, beloved,
building yourselves up in your most holy faith and praying in the Holy Spirit,
21 keep yourselves in the love of God, waiting for the mercy of our Lord Jesus Christ that leads to eternal life.